Baclofen

Brand name: Baclofen

Description

Muscle Relaxant
Conditions, accompanied by increased muscle tone, may be related to the following diseases: multiple sclerosis, spinal cord diseases, including infectious, traumatic failure or degenerative, cerebral palsy, stroke, head injuries, meningitis, as well as in alcoholism
Brands: Lioresal And Gablofen
Availability: Prescription needed
Pregnancy: Consult a doctor
Alcohol: Consult a doctor before drinking alcohol
Side Effects: Mental Depression Or Other Mood Changes, Irregular, Fast Or Slow, Or Shallow Breathing, Muscle Pain Or Weakness
Interactions: Lyrica (pregabalin), Norco (acetaminophen / Hydrocodone), Xanax (alprazolam)
For informational purposes only. Consult your local medical authority for advice.

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Having a therapy that has been shown baclofen and kidney function to address multiple symptoms of Rett syndrome provides a promising treatment option that may lead to meaningful impact for patients and their families. Findings showed that treatment with trofinetide led to statistically significant improvements on the Rett Syndrome Behaviour Questionnaire total score and the Clinical Global Impression-Improvement score at week 12 compared with placebo (coprimary endpoints). The dosage is determined by patient weight and can be administered orally or via gastrostomy tube.

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The most common adverse reactions reported with trofinetide led to statistically significant improvements on the Rett Syndrome Behaviour Questionnaire total score and the Clinical Global Impression-Improvement score at week 12 compared with placebo (coprimary endpoints).

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